Maco1 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Involved in brain development. Located in several cellular components, including axon; neuron projection terminus; and nuclear membrane. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; cortical plate; and testis. Orthologous to human MACO1 (macoilin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Maco1 |
| Official Name | macoilin 1 [Source:MGI Symbol;Acc:MGI:1913396] |
| Ensembl ID | ENSMUSG00000028826 |
| Bio databases IDs | |
| Aliases | macoilin 1 |
| Synonyms | 1110007C24RIK, 9230118A01Rik, C61, FLJ10747, MACOILIN, macoilin 1, TMEM57 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Maco1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lycopene cyclase
- protein binding
- Macoilin family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell surface
- nuclear envelope
- neurites
- nerve ending
- synapse
- rough endoplasmic reticulum membrane
- axons
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Maco1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chemotaxis
- neuronal signal transduction
- brain development
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear membrane
- rough endoplasmic reticulum membrane
- synapse
- axon
- neuron projection terminus
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding