Nudc Gene Summary [Mouse]
Predicted to enable unfolded protein binding activity. Predicted to be involved in several processes, including mitotic metaphase chromosome alignment; mitotic spindle organization; and protein folding. Predicted to be located in cytosol; midbody; and mitotic spindle. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human NUDC (nuclear distribution C, dynein complex regulator). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nudc |
| Official Name | nudC nuclear distribution protein [Source:MGI Symbol;Acc:MGI:106014] |
| Ensembl ID | ENSMUSG00000028851 |
| Bio databases IDs | |
| Aliases | nudC nuclear distribution protein |
| Synonyms | c15, HNUDC, LOC100911422, MNUDC, NPD011, nuclear distribution C, dynein complex regulator, nudC nuclear distribution protein, SIG-92, Silg92 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nudc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CS domain
- N-terminal conserved domain of Nudc
- alpha-crystallin Hsps/p23-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- expression in
- formation
- formation in
- migration
- maturation
- transport in
- misalignment in
- organization
- misalignment
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- spindle apparatus
- Nucleus
- midbody
- cytosol
- nucleoplasm
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nudc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- mitotic spindle organization
- nuclear migration
- protein folding
- mitotic metaphase plate congression
- response to peptide hormone stimulus
Cellular Component
Where in the cell the gene product is active
- mitotic spindle
- cytoplasm
- spindle
- cytosol
- midbody
- microtubule
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- cadherin binding
- unfolded protein binding