Kcnip4 Gene Summary [Mouse]
Enables calcium ion binding activity and potassium channel regulator activity. Involved in regulation of potassium ion transmembrane transport. Part of voltage-gated potassium channel complex. Is expressed in brain; dorsal root ganglion; meninges; retina; and spinal cord. Orthologous to human KCNIP4 (potassium voltage-gated channel interacting protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnip4 |
| Official Name | Kv channel interacting protein 4 [Source:MGI Symbol;Acc:MGI:1933131] |
| Ensembl ID | ENSMUSG00000029088 |
| Bio databases IDs | |
| Aliases | Kv channel interacting protein 4 |
| Synonyms | AV032399, CALP, Calp250, KCHIP4, KChIP4a, Kv channel interacting protein 4, potassium voltage-gated channel interacting protein 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcnip4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF-hand domain pair
- EF hand
- potassium channel regulator
- calcium ion binding
- EFh
- protein binding
- ion channel
- EFh_PI-PLC
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cytosol
- peroxisomes
- perikaryon
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcnip4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transmembrane transport
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- peroxisome
- dendrite
- cytoplasm
- voltage-gated potassium channel complex
- cytosol
- endoplasmic reticulum
- neuronal cell body
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- potassium channel activity
- potassium channel regulator activity