Fam120b Gene Summary [Mouse]
Acts upstream of or within fat cell differentiation and peroxisome proliferator activated receptor signaling pathway. Located in nucleus. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human FAM120B (family with sequence similarity 120 member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam120b |
| Official Name | family with sequence similarity 120, member B [Source:MGI Symbol;Acc:MGI:1914794] |
| Ensembl ID | ENSMUSG00000014763 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 120, member B |
| Synonyms | 4932442K08Rik, AW049283, CCPG, dJ894D12.1, family with sequence similarity 120 member B, family with sequence similarity 120, member B, KIAA1838, LOC105378156, mKIAA1838, PGCC1, RGD1310304, SAN1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam120b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-terminal transactivation domain
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- insomnia
- organismal death
- schizophrenia
- Behcet disease
- dementia
- idiopathic dilated cardiomyopathy
- esophageal squamous cell carcinoma
- esophageal squamous cell cancer
role in cell
- phosphorylation in
- activation in
- proliferation
- expression in
- invasion by
- differentiation
- processing in
- ubiquitination in
- degradation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam120b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fat cell differentiation
- peroxisome proliferator activated receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding