Slc30a9 Gene Summary [Mouse]
Enables chromatin binding activity; nuclear receptor binding activity; and transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytoplasmic vesicle; cytoskeleton; and mitochondrial membrane. Predicted to be active in endoplasmic reticulum. Is expressed in cranial ganglion and urethra. Orthologous to human SLC30A9 (solute carrier family 30 member 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc30a9 |
| Official Name | solute carrier family 30 (zinc transporter), member 9 [Source:MGI Symbol;Acc:MGI:1923690] |
| Ensembl ID | ENSMUSG00000029221 |
| Bio databases IDs | |
| Aliases | solute carrier family 30 (zinc transporter), member 9 |
| Synonyms | 2310024J23Rik, BILAPES, C4orf1, GAC63, HUEL, solute carrier family 30 member 9, solute carrier family 30 (zinc transporter), member 9, ZNT9 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc30a9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DBD_XPA-like
- cation diffusion facilitator family transporter
- ligand-dependent nuclear receptor interactor
- transcription co-activator
- chromatin binding
- zinc ion transporter
- Cation efflux family
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- Birk-Landau-Perez syndrome
- major depression
regulates
- DNA promoter
- DNA endogenous promoter
- RNA polymerase II
- CYP1A1
- Zn2+
role in cell
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoskeleton
- Cytoplasm
- Endoplasmic Reticulum
- Mitochondria
- mitochondrial membrane
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc30a9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- zinc ion transport
- cellular zinc ion homeostasis
- nucleotide-excision repair
- zinc ion transmembrane transport
- regulation of mitochondrion organization
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- mitochondrial membrane
- cytoplasmic vesicle
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- ligand-dependent nuclear receptor binding
- antiporter activity
- zinc ion transmembrane transporter activity
- ligand-dependent nuclear receptor transcription coactivator activity
- chromatin binding