Sult1b1 Gene Summary [Mouse]
Enables aryl sulfotransferase activity. Involved in sulfation and thyroid hormone metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SULT1B1 (sulfotransferase family 1B member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sult1b1 |
| Official Name | sulfotransferase family 1B, member 1 [Source:MGI Symbol;Acc:MGI:2136282] |
| Ensembl ID | ENSMUSG00000029269 |
| Bio databases IDs | |
| Aliases | sulfotransferase family 1B, member 1 |
| Synonyms | LOC64305, ST1B1, ST1B2, St1b3, St2b2, sulfotransferase family 1B member 1, sulfotransferase family 1B, member 1, sulphotransferase family 1B member 1, sulphotransferase family 1B, member 1, SULT1B2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sult1b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfotransferase
- Sulfotransferase domain
- enzyme
- protein binding
- aryl sulfotransferase
- Sulfotransferase family
Pathways
Biological processes and signaling networks where the Sult1b1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine leiomyoma
- leiomyomatosis
- primary pulmonary hypertension
- nicotine dependence
- high-grade serous ovarian cancer
regulates
- thyroid hormone
- ethanol
- 8-hydroxy-6-formylindolo[3,2-b]carbazole
- xenobiotic
- phenol derivative
- flavonoid
- 2-hydroxy-6-formylindolo[3,2-b]carbazole
- raloxifene
- phosphoadenosine phosphosulfate
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sult1b1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell differentiation
- phenol-containing compound metabolic process
- xenobiotic metabolic process
- ethanol catabolic process
- 3'-phosphoadenosine 5'-phosphosulfate metabolic process
- sulfation
- flavonoid metabolic process
- cellular biogenic amine metabolic process
- thyroid hormone metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- aryl sulfotransferase activity
- sulfotransferase activity