Zcchc8 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Is expressed in several structures, including blastocyst; early embryo; eye; secondary oocyte; and trunk somite. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zcchc8 |
| Official Name | zinc finger, CCHC domain containing 8 [Source:MGI Symbol;Acc:MGI:1917900] |
| Ensembl ID | ENSMUSG00000029427 |
| Bio databases IDs | |
| Aliases | zinc finger, CCHC domain containing 8 |
| Synonyms | 5730565F05Rik, LOC100507874, PFBMFT5, zinc finger, CCHC domain containing 8, zinc finger CCHC-type containing 8 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zcchc8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc knuckle
- zinc finger
- PSP
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- catalytic step 2 spliceosome
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zcchc8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- snRNA catabolic process
- mRNA 3'-end processing
- RNA processing
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- catalytic step 2 spliceosome
- nucleolus
- TRAMP complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- RNA binding
- protein binding