Rbm7 Gene Summary [Mouse]

Predicted to enable 14-3-3 protein binding activity and RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome and snRNA catabolic process. Located in nucleus. Orthologous to human RBM7 (RNA binding motif protein 7). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rbm7
Official Name
RNA binding motif protein 7 [Source:MGI Symbol;Acc:MGI:1914260]
Ensembl ID
ENSMUSG00000042396
Bio databases IDs NCBI: 67010 Ensembl: ENSMUSG00000042396
Aliases RNA binding motif protein 7
Synonyms 1200007M24Rik, 1500011D06RIK, RNA binding motif protein 7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbm7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • snRNA binding
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nonalcoholic fatty liver disease
  • bleomycin-induced pulmonary fibrosis
  • pulmonary fibrosis
  • short telomere syndrome
  • infection by HIV-1
regulated by
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbm7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • meiotic cell cycle
  • regulation of alternative nuclear mRNA splicing, via spliceosome
  • snRNA catabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • pre-mRNA intronic binding
  • protein binding
  • RNA binding
  • single-stranded RNA binding
  • snRNA binding
  • 14-3-3 protein binding