Cyp2w1 Gene Summary [Mouse]
Predicted to enable heme binding activity; monooxygenase activity; and retinoid binding activity. Predicted to be involved in several processes, including aflatoxin metabolic process; phospholipid metabolic process; and retinoic acid catabolic process. Predicted to be located in cell surface and endoplasmic reticulum lumen. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in colon; large intestine; and small intestine. Orthologous to human CYP2W1 (cytochrome P450 family 2 subfamily W member 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Retained Intron |
| Official Symbol | Cyp2w1 |
| Official Name | cytochrome P450, family 2, subfamily w, polypeptide 1 [Source:MGI Symbol;Acc:MGI:3616076] |
| Ensembl ID | ENSMUSG00000029541 |
| Bio databases IDs | |
| Aliases | cytochrome P450, family 2, subfamily w, polypeptide 1 |
| Synonyms | cytochrome P450 family 2 subfamily W member 1, cytochrome P450, family 2, subfamily w, polypeptide 1, Gm455 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cyp2w1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome P450 (CYP) superfamily
- Cytochrome P450
- binding protein
- all-trans retinal binding
- retinol binding
- retinoic acid 4-hydroxylase
- monooxygenase
- enzyme
- retinoid binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell surface
- cellular membrane
- endoplasmic reticulum membrane
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cyp2w1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- organic acid metabolic process
- aflatoxin metabolic process
- xenobiotic metabolic process
- retinoic acid catabolic process
- phospholipid metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum lumen
- cytoplasm
- intracellular membrane-bounded organelle
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- all-trans retinal binding
- retinoic acid binding
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- iron ion binding
- retinoic acid 4-hydroxylase activity
- monooxygenase activity
- heme binding