Abtb1 Gene Summary [Mouse]
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytosol; nucleolus; and plasma membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; ganglia; genitourinary system; sensory organ; and skeleton. Orthologous to human ABTB1 (ankyrin repeat and BTB domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abtb1 |
| Official Name | ankyrin repeat and BTB (POZ) domain containing 1 [Source:MGI Symbol;Acc:MGI:1933148] |
| Ensembl ID | ENSMUSG00000030083 |
| Bio databases IDs | |
| Aliases | ankyrin repeat and BTB (POZ) domain containing 1 |
| Synonyms | ankyrin repeat and BTB domain containing 1, BPOZ, BTB3, BTBD21, EF1ABP, PP2259 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abtb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- BTB/POZ domain
- protein binding
- BACK (BTB and C-terminal Kelch) domain
- translation regulator
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Abtb1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- translational elongation
Cellular Component
Where in the cell the gene product is active
- ubiquitin ligase complex
- cytoplasm
- cytosol
- nucleolus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- translation elongation factor activity