Slc41a3 Gene Summary [Mouse]

Predicted to enable magnesium:sodium antiporter activity. Predicted to be involved in mitochondrial magnesium ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system; eye; hemolymphoid system; liver; and nervous system. Orthologous to human SLC41A3 (solute carrier family 41 member 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc41a3
Official Name
solute carrier family 41, member 3 [Source:MGI Symbol;Acc:MGI:1918949]
Ensembl ID
ENSMUSG00000030089
Bio databases IDs NCBI: 71699 Ensembl: ENSMUSG00000030089
Aliases solute carrier family 41, member 3
Synonyms 1010001P06RIK, SLC41A1-L2, solute carrier family 41 member 3, solute carrier family 41, member 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc41a3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • sodium ion transporter
  • antiporter
  • protein binding
  • magnesium ion transporter
  • metal ion transporter
  • transporter
  • Divalent cation transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • Bell palsy
regulated by
role in cell
  • migration
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc41a3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial magnesium ion transport
  • sodium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • plasma membrane
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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