Wbp11 Gene Summary [Mouse]
Enables protein phosphatase regulator activity. Acts upstream of or within RNA splicing. Located in cytoplasm and nuclear speck. Is expressed in several structures, including blood; embryo ectoderm; embryo mesenchyme; extraembryonic component; and heart. Orthologous to human WBP11 (WW domain binding protein 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wbp11 |
| Official Name | WW domain binding protein 11 [Source:MGI Symbol;Acc:MGI:1891823] |
| Ensembl ID | ENSMUSG00000030216 |
| Bio databases IDs | |
| Aliases | WW domain binding protein 11 |
| Synonyms | 2510026P17Rik, BUG13, CFAP90, D6Wsu113e, FAP90, LOC100910115, NPWBP, PPP1R165, SIPP1, VCTERL, VCTRL, Wbp11l1, WW domain binding protein 11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wbp11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WW domain binding protein 11
- single-stranded DNA binding
- phosphatase
- protein phosphatase regulator
- WW domain binding
- protein binding
- proline rich domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung cancer
- vertebral, cardiac, tracheoesophageal, renal and limb defects
- hereditary disorder
- disease-free survival
role in cell
- expression in
- proliferation
- migration
- duplication in
- duplication
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- Cytoplasm
- cytosol
- spliceosomes
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wbp11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- rRNA processing
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- intracellular membrane-bounded organelle
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- WW domain binding
- single-stranded DNA binding