Pop4 Gene Summary [Mouse]
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Is expressed in sensory organ and skeleton. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pop4 |
| Official Name | processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1913411] |
| Ensembl ID | ENSMUSG00000030423 |
| Bio databases IDs | |
| Aliases | processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) |
| Synonyms | 1110023P21Rik, POP4 homolog, ribonuclease P/MRP subunit, processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae), RPP29 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pop4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribonuclease P/MRP, subunit p29
- ribonuclease P
- enzyme
- protein binding
- POP4
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleolar region
- dense fibrillar component
- nucleoplasm
- nucleoli
- coiled body
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pop4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA processing
- tRNA 5'-leader removal
Cellular Component
Where in the cell the gene product is active
- ribonuclease MRP complex
- multimeric ribonuclease P complex
- nucleolus
- ribonuclease P complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ribonuclease P activity
- protein binding
- ribonuclease P RNA binding