Pcdhgb4 Gene Summary [Mouse]

Predicted to be involved in cell adhesion. Located in membrane. Is expressed in brain. Orthologous to human PCDHGB4 (protocadherin gamma subfamily B, 4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Pcdhgb4
Official Name
protocadherin gamma subfamily B, 4 [Source:MGI Symbol;Acc:MGI:1935173]
Ensembl ID
ENSMUSG00000103585
Bio databases IDs NCBI: 93701 Ensembl: ENSMUSG00000103585
Aliases protocadherin gamma subfamily B, 4
Synonyms CDH20, FIB2, PCDH-GAMMA-B4, PCDH-γ-B4, protocadherin gamma subfamily B, 4, protocadherin γ subfamily B, 4
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdhgb4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin-like
  • Cadherin repeat-like domain
  • protein binding
  • Cadherin cytoplasmic C-terminal

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • atopic dermatitis
regulates
role in cell
  • quantity
  • apoptosis
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdhgb4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • calcium-dependent cell-cell adhesion
  • nervous system development
  • cell adhesion
  • homophilic cell adhesion

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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