Anks4b Gene Summary [Mouse]
Acts upstream of or within response to endoplasmic reticulum stress. Located in several cellular components, including brush border; endoplasmic reticulum membrane; and microvillus. Is expressed in alimentary system; cochlea epithelium; genitourinary system; liver; and lung epithelium. Orthologous to human ANKS4B (ankyrin repeat and sterile alpha motif domain containing 4B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Anks4b |
| Official Name | ankyrin repeat and sterile alpha motif domain containing 4B [Source:MGI Symbol;Acc:MGI:1919324] |
| Ensembl ID | ENSMUSG00000030909 |
| Bio databases IDs | |
| Aliases | ankyrin repeat and sterile alpha motif domain containing 4B |
| Synonyms | 2010013E14Rik, ankyrin repeat and sterile alpha motif domain containing 4B, ankyrin repeat and sterile α motif domain containing 4B, HARP, LOC103691218 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Anks4b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sterile alpha motif
- transcription regulator
- Ankyrin repeats (many copies)
- SAM (Sterile alpha motif )
- Ankyrin repeats (3 copies)
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- endoplasmic reticulum membrane
- brush border
- microvilli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Anks4b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- macromolecular complex assembly
- cell differentiation
- response to endoplasmic reticulum stress
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- brush border
- microvillus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding