Galnt7 Gene Summary [Mouse]

Enables polypeptide N-acetylgalactosaminyltransferase activity. Acts upstream of or within protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human GALNT7 (polypeptide N-acetylgalactosaminyltransferase 7). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Galnt7
Official Name
polypeptide N-acetylgalactosaminyltransferase 7 [Source:MGI Symbol;Acc:MGI:1349449]
Ensembl ID
ENSMUSG00000031608
Bio databases IDs NCBI: 108150 Ensembl: ENSMUSG00000031608
Aliases polypeptide N-acetylgalactosaminyltransferase 7
Synonyms GALNAC-T7, N-ACETYLGALACTOSAMINYLTRANSFERASE 7, polypeptide N-acetylgalactosaminyltransferase 7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Galnt7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ricin-type beta-trefoil lectin domain
  • Glycosyl transferase family 2
  • Ricin-type beta-trefoil
  • polypeptide N-acetylgalactosaminyltransferase
  • N-terminal domain of galactosyltransferase
  • enzyme
  • ricin B-type lectin domain, beta-trefoil fold
  • glycosyltransferase family A

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
regulates
  • AKT
  • O-glycan
  • carbohydrate
role in cell
  • phosphorylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Galnt7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • carbohydrate metabolic process
  • protein O-linked glycosylation
  • O-glycan processing

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • membrane
  • Golgi apparatus
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • carbohydrate binding
  • polypeptide N-acetylgalactosaminyltransferase activity

Gene-Specific Assays for Results You Can Trust

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