Tbc1d9 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Is expressed in dentate gyrus subgranular zone. Orthologous to human TBC1D9 (TBC1 domain family member 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tbc1d9 |
| Official Name | TBC1 domain family, member 9 [Source:MGI Symbol;Acc:MGI:1918560] |
| Ensembl ID | ENSMUSG00000031709 |
| Bio databases IDs | |
| Aliases | TBC1 domain family, member 9 |
| Synonyms | 4933431N12RIK, AI847101, GRAMD9, KIAA0882, MDR1, RGD1308221, TBC1 domain family member 9, TBC1 domain family, member 9 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tbc1d9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab-GTPase-TBC domain
- RNA recognition motif (RRM) superfamily
- Domain in Tre-2, BUB2p, and Cdc16p
- protein binding
- Pleckstrin homology-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- primary biliary cirrhosis
- prostatic carcinoma
- prostate cancer
- breast carcinoma
- COVID-19
- medullary thyroid carcinoma
- medullary thyroid cancer
regulates
- grepafloxacin
role in cell
- survival
- autophagy in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tbc1d9 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- GTPase activator activity