Lctl Gene Summary [Mouse]

Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Involved in lens morphogenesis in camera-type eye. Located in brush border and endoplasmic reticulum. Orthologous to human LCTL (lactase like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lctl
Official Name
lactase-like [Source:MGI Symbol;Acc:MGI:2183549]
Ensembl ID
ENSMUSG00000032401
Bio databases IDs NCBI: 235435 Ensembl: ENSMUSG00000032401
Aliases lactase-like
Synonyms E130104I05Rik, KLG, KLPH, lactase-like
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lctl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme
  • Glycosyl hydrolase family 1
  • beta-galactosidase
  • Glycosyl hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • kidney carcinoma
  • renal cancer
  • insomnia
regulated by
  • beta-carotene
  • tributyltin
  • AGN194204
  • CELF1
regulates
role in cell
  • downregulation in
  • induction in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Endoplasmic Reticulum
  • brush border

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lctl gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • carbohydrate metabolic process
  • visual perception
  • lens morphogenesis in camera-type eye

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • brush border

Molecular Function

What the gene product does at the molecular level
  • beta-glucosidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.