Ilvbl Gene Summary [Mouse]
Predicted to enable acetolactate synthase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in L-valine biosynthetic process; fatty acid alpha-oxidation; and isoleucine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of acetolactate synthase complex. Orthologous to human ILVBL (ilvB acetolactate synthase like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ilvbl |
| Official Name | ilvB (bacterial acetolactate synthase)-like [Source:MGI Symbol;Acc:MGI:1351911] |
| Ensembl ID | ENSMUSG00000032763 |
| Bio databases IDs | |
| Aliases | ilvB (bacterial acetolactate synthase)-like |
| Synonyms | 209L8, 5830463I21, AHAS, HACL1L, HACL2, ILV2H, ilvB acetolactate synthase like, ilvB (bacterial acetolactate synthase)-like |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ilvbl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
- Thiamine pyrophosphate enzyme, central domain
- TPP_enzymes
- acetolactate synthase, large subunit, biosynthetic type
- enzyme
- protein binding
- acetolactate synthase, catabolic
- thiamine pyrophosphate-dependent enzyme pyrimidine binding domain
- Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
- pyruvate oxidase
- acetolactate synthase large subunit
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ilvbl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- isoleucine biosynthetic process
- valine biosynthetic process
- fatty acid alpha-oxidation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- acetolactate synthase complex
- membrane
Molecular Function
What the gene product does at the molecular level
- thiamine pyrophosphate binding
- magnesium ion binding
- acetolactate synthase activity
- protein binding
- flavin adenine dinucleotide binding
- lyase activity