Camkv Gene Summary [Mouse]
Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Involved in modulation of chemical synaptic transmission and regulation of modification of postsynaptic structure. Is active in glutamatergic synapse. Is expressed in brain; phalanx; and spinal cord. Orthologous to human CAMKV (CaM kinase like vesicle associated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Camkv |
| Official Name | CaM kinase-like vesicle-associated [Source:MGI Symbol;Acc:MGI:2384296] |
| Ensembl ID | ENSMUSG00000032936 |
| Bio databases IDs | |
| Aliases | CaM kinase-like vesicle-associated |
| Synonyms | 1G5, BB074618, CaM kinase-like vesicle-associated, VACAMKL |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Camkv often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein Kinases, catalytic domain
- calmodulin binding
- Protein kinase domain
- Spt5 C-terminal nonapeptide repeat binding Spt4
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pain
- osteoarthritis
- pervasive developmental disorder
- Huntington disease
- Alzheimer disease
- inflammatory bowel disease
- attention deficit hyperactivity disorder
- diabetic peripheral neuropathy
regulates
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- postsynaptic region
- growth cone
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Camkv gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of synaptic transmission
- peptidyl-serine phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- intracellular
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- calmodulin binding
- calmodulin-dependent protein kinase activity