Tpsg1 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human TPSG1 (tryptase gamma 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tpsg1 |
| Official Name | tryptase gamma 1 [Source:MGI Symbol;Acc:MGI:1349391] |
| Ensembl ID | ENSMUSG00000033200 |
| Bio databases IDs | |
| Aliases | tryptase gamma 1 |
| Synonyms | PRSS31, TMT, trpA, tryptase gamma 1, tryptase γ 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tpsg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine-type peptidase
- tryptase
- peptidase
- Domain of unknown function (DUF1986)
- protein binding
Pathways
Biological processes and signaling networks where the Tpsg1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
- plasma membrane extracellular face
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tpsg1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular space
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- serine-type peptidase activity
- serine-type endopeptidase activity