Mcee Gene Summary [Mouse]
Predicted to enable methylmalonyl-CoA epimerase activity. Predicted to be involved in L-methylmalonyl-CoA metabolic process. Located in mitochondrion. Is expressed in central nervous system; choroid plexus; and nervous system. Orthologous to human MCEE (methylmalonyl-CoA epimerase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Mcee |
| Official Name | methylmalonyl CoA epimerase [Source:MGI Symbol;Acc:MGI:1920974] |
| Ensembl ID | ENSMUSG00000033429 |
| Bio databases IDs | |
| Aliases | methylmalonyl CoA epimerase |
| Synonyms | 1110007A04RIK, GLOD2, MCE, methylmalonyl-CoA epimerase, MMCE |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mcee often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glyoxalase I/type I extradiol dioxygenase/antibiotic resistance protein metal-binding domain
- methylmalonyl-CoA epimerase
- enzyme
- protein binding
- Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Pathways
Biological processes and signaling networks where the Mcee gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mcee gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- short-chain fatty acid catabolic process
- L-methylmalonyl-CoA metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- methylmalonyl-CoA epimerase activity