Rps10 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; translation at postsynapse; and translation at presynapse. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in several structures, including branchial arch; jaw; limb; maxillary process; and sensory organ. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to human RPS10 (ribosomal protein S10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps10 |
| Official Name | ribosomal protein S10 [Source:MGI Symbol;Acc:MGI:1914347] |
| Ensembl ID | ENSMUSG00000052146 |
| Bio databases IDs | |
| Aliases | ribosomal protein S10 |
| Synonyms | 2210402A09RIK, 40S RIBOSOMAL protein S10, DBA9, eS10, ribosomal protein S10, S10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- structural constituent of ribosome
- Plectin/S10 domain
- protein binding
Pathways
Biological processes and signaling networks where the Rps10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Diamond-Blackfan anemia
- diamond-blackfan anemia type 9
regulates
- RNR
- Ribosomal Subunit 40s
role in cell
- proliferation
- replication in
- nuclear export in
- assembly
- assembly in
- synthesis in
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- detergent resistant lipid raft fraction
- ribosome
- cytosol
- granular components
- nucleoplasm
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- focal adhesion
- cytosolic ribosome
- cytosolic small ribosomal subunit
- cytoplasm
- membrane
- cytosol
- ribosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome