Rbm46 Gene Summary [Mouse]
Enables RNA binding activity. Involved in several processes, including cell cycle switching, mitotic to meiotic cell cycle; meiotic nuclear division; and spermatid differentiation. Acts upstream of or within mRNA stabilization and trophectodermal cell differentiation. Located in cytoplasm and nucleus. Is expressed in central nervous system; craniocervical region bone; dorsal root ganglion; lung; and rib. Orthologous to human RBM46 (RNA binding motif protein 46). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rbm46 |
| Official Name | RNA binding motif protein 46 [Source:MGI Symbol;Acc:MGI:3645057] |
| Ensembl ID | ENSMUSG00000033882 |
| Bio databases IDs | |
| Aliases | RNA binding motif protein 46 |
| Synonyms | CT68, EG633285, Gm761, MGC271016, RGD1560205, RNA binding motif protein 46 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbm46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- double-stranded RNA binding motif (DSRM) superfamily
- protein binding
- heterogeneous nuclear ribonucleoprotein R, Q family
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbm46 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- female meiosis
- oogenesis
- male meiosis
- spermatogenesis
- mRNA stabilization
- spermatid differentiation
- cell cycle switching, mitotic to meiotic cell cycle
- trophectodermal cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- mRNA binding