Hsdl1 Gene Summary [Mouse]

Located in mitochondrion. Is expressed in central nervous system; retina inner nuclear layer; retina layer; and retina outer nuclear layer. Orthologous to human HSDL1 (hydroxysteroid dehydrogenase like 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hsdl1
Official Name
hydroxysteroid dehydrogenase like 1 [Source:MGI Symbol;Acc:MGI:1919802]
Ensembl ID
ENSMUSG00000034189
Bio databases IDs NCBI: 72552 Ensembl: ENSMUSG00000034189
Aliases hydroxysteroid dehydrogenase like 1
Synonyms 2700067E09Rik, hydroxysteroid dehydrogenase like 1, RGD1308433, SDR12C3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hsdl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • enzyme
  • protein binding
  • short chain dehydrogenase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • OGA
  • methylphenidate
role in cell
  • cytotoxic T lymphocyte response

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intermediate filament cytoskeleton
  • intracellular membrane-bounded organelle
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Hsdl1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • intermediate filament cytoskeleton
  • intracellular membrane-bounded organelle
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • steroid dehydrogenase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.