Dynlrb2 Gene Summary [Mouse]

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Part of cytoplasmic dynein complex. Is expressed in several structures, including brain ventricle and choroid plexus; lung; palatal shelf mesenchyme; and sensory organ. Orthologous to human DYNLRB2 (dynein light chain roadblock-type 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Dynlrb2
Official Name
dynein light chain roadblock-type 2 [Source:MGI Symbol;Acc:MGI:1922715]
Ensembl ID
ENSMUSG00000034467
Bio databases IDs NCBI: 75465 Ensembl: ENSMUSG00000034467
Aliases dynein light chain roadblock-type 2
Synonyms 1700009A04Rik, DNCL2B, DNLC2B, dynein light chain roadblock-type 2, ROADBLOCK-2, ROBLD2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dynlrb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Roadblock/LC7 domain

Pathways

Biological processes and signaling networks where the Dynlrb2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ciliary tip
  • cilia

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dynlrb2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule-based movement

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic dynein complex
  • centrosome
  • cytoplasm
  • cilium
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • microtubule motor activity
  • dynein intermediate chain binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.