Washc4

Involved in endosomal transport. Acts upstream of or within several processes, including endolysosomal toll-like receptor signaling pathway; neuromuscular process; and regulation of protein complex stability. Located in endosome. Part of WASH complex. Is expressed in early conceptus and oocyte. Used to study Wiskott-Aldrich syndrome. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 43. Orthologous to human WASHC4 (WASH complex subunit 4). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Washc4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Washc4 gene, providing context for its role in the cell.