Gpatch8 Gene Summary [Mouse]
Enables mRNA binding activity. Acts upstream of or within hemopoiesis and mRNA splicing, via spliceosome. Predicted to be active in nucleus. Is expressed in brain; cerebellum; and forebrain. Orthologous to human GPATCH8 (G-patch domain containing 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpatch8 |
| Official Name | G patch domain containing 8 [Source:MGI Symbol;Acc:MGI:1918667] |
| Ensembl ID | ENSMUSG00000034621 |
| Bio databases IDs | |
| Aliases | G patch domain containing 8 |
| Synonyms | 5430405G24RIK, AU018890, Fbm1, GPATC8, G-patch domain containing 8, KIAA0553, mKIAA0553 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpatch8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-patch domain
- Zinc-finger double-stranded RNA-binding
- mRNA binding
- U1 zinc finger
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpatch8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- metal ion binding