Tmx4 Gene Summary [Mouse]
Predicted to enable disulfide oxidoreductase activity. Located in nuclear inner membrane. Is expressed in future spinal cord. Orthologous to human TMX4 (thioredoxin related transmembrane protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmx4 |
| Official Name | thioredoxin-related transmembrane protein 4 [Source:MGI Symbol;Acc:MGI:106558] |
| Ensembl ID | ENSMUSG00000034723 |
| Bio databases IDs | |
| Aliases | thioredoxin-related transmembrane protein 4 |
| Synonyms | 2810417D04Rik, 4930500L08Rik, D2Bwg1356e, DJ971N18.2, mKIAA1162, PDIA14, RGD1305146, thioredoxin-related transmembrane protein 4, TXNDC13 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmx4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- enzyme
- thioredoxin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- cellular membrane
- Nucleus
- Endoplasmic Reticulum
- inner nuclear membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmx4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nuclear inner membrane
- endomembrane system
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- disulfide oxidoreductase activity