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This gene encodes a protein that contains an ubiquitin-like domain. This protein may be involved in the regulation of brain development as inferred by its high expression level in the embryonic midbrain. This protein has been found to negatively regulate glucokinase activity and insulin secretion in pancreatic beta cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Midn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
kinase binding
Ubl1_cv_Nsp3_N-like
protein binding
ubiquitin-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Nucleus
Cytoplasm
cytoplasmic particles
cytosol
nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Midn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
negative regulation of glucokinase activity
negative regulation of insulin secretion
proteasomal ubiquitin-independent protein catabolic process
Cellular Component
Where in the cell the gene product is active
nucleus
cytoplasm
cytosol
nucleolus
Molecular Function
What the gene product does at the molecular level
protein binding
kinase binding
binding, bridging
Gene-Specific Assays for Results You Can Trust
Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.