Midn Gene Summary [Rat]
Enables kinase binding activity. Acts upstream of or within negative regulation of glucokinase activity and negative regulation of insulin secretion. Predicted to be located in cytosol and nucleolus. Predicted to be active in nucleus. Orthologous to human MIDN (midnolin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Midn |
| Official Name | midnolin [Source:RGD Symbol;Acc:1309629] |
| Ensembl ID | ENSRNOG00000015434 |
| Bio databases IDs | |
| Aliases | midnolin |
| Synonyms | 3000003C15Rik, midnolin, Stx |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Midn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase binding
- Ubl1_cv_Nsp3_N-like
- protein binding
- ubiquitin-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytoplasmic particles
- cytosol
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Midn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of glucokinase activity
- negative regulation of insulin secretion
- proteasomal ubiquitin-independent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- kinase binding
- binding, bridging