Nepro Gene Summary [Mouse]
Acts upstream of or within negative regulation of neuron differentiation and positive regulation of Notch signaling pathway. Located in nucleolus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in anauxetic dysplasia 3. Orthologous to human NEPRO (nucleolus and neural progenitor protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nepro |
| Official Name | nucleolus and neural progenitor protein [Source:MGI Symbol;Acc:MGI:2384836] |
| Ensembl ID | ENSMUSG00000036208 |
| Bio databases IDs | |
| Aliases | nucleolus and neural progenitor protein |
| Synonyms | ANXD3, BC027231, C3orf17, DKFZP434F2021, NET17, nucleolus and neural progenitor protein, RGD1311458 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nepro often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RMP1_RBD
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nepro gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of neuron differentiation
- positive regulation of Notch signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus