Tmem260 Gene Summary [Mouse]
Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in protein maturation. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in T-cell non-Hodgkin lymphoma; non-Hodgkin lymphoma; and stomach cancer. Orthologous to human TMEM260 (transmembrane protein 260). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem260 |
| Official Name | transmembrane protein 260 [Source:MGI Symbol;Acc:MGI:2443219] |
| Ensembl ID | ENSMUSG00000036339 |
| Bio databases IDs | |
| Aliases | transmembrane protein 260 |
| Synonyms | 5930435P15, 6720456H20Rik, C14orf101, LOC686366, RGD1562018, SHDRA, transmembrane protein 260 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem260 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF2723)
- enzyme
- dolichyl-phosphate-mannose-protein mannosyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem260 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein maturation
- protein O-linked mannosylation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- dolichyl-phosphate-mannose-protein mannosyltransferase activity