Cd96 Gene Summary [Mouse]
Acts upstream of or within negative regulation of natural killer cell cytokine production; negative regulation of type II interferon production; and response to lipopolysaccharide. Predicted to be located in cytoplasm. Is expressed in several structures, including blood; central nervous system; ganglia; heart; and lung. Human ortholog(s) of this gene implicated in C syndrome. Orthologous to human CD96 (CD96 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd96 |
| Official Name | CD96 antigen [Source:MGI Symbol;Acc:MGI:1934368] |
| Ensembl ID | ENSMUSG00000022657 |
| Bio databases IDs | |
| Aliases | CD96 antigen |
| Synonyms | 1700109I12RIK, CD96 antigen, CD96 molecule, TACTILE |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd96 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- immunoglobulin G-like domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- idiopathic scoliosis
- survival
- insulin-dependent diabetes mellitus
- psoriasis like inflammation
- C syndrome
- proliferative diabetic retinopathy
- dementia
role in cell
- expression in
- adhesion
- function
- cytotoxicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd96 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
- inflammatory response
- immune response
- negative regulation of natural killer cell cytokine production
- cell adhesion
- response to lipopolysaccharide
- negative regulation of interferon-gamma production
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- plasma membrane