Gpr101 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and positive regulation of MAPK cascade. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in growth hormone secreting pituitary adenoma 2. Orthologous to human GPR101 (G protein-coupled receptor 101). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gpr101
Official Name
G protein-coupled receptor 101 [Source:MGI Symbol;Acc:MGI:2685211]
Ensembl ID
ENSMUSG00000036357
Bio databases IDs NCBI: 245424 Ensembl: ENSMUSG00000036357
Aliases G protein-coupled receptor 101
Synonyms Gm365, GPCR6, G protein-coupled receptor 101, PAGH2, PITA2, RGD1564196
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr101 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • protein binding
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gpr101 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • growth hormone-secreting pituitary adenoma 2
regulated by
role in cell
  • growth
  • cisplatin sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr101 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • adenylate cyclase-activating adrenergic receptor signaling pathway
  • positive regulation of MAPK cascade

Cellular Component

Where in the cell the gene product is active
  • receptor complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.