GPR101
GPR101 Gene Summary
The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]
Details
| Type | Protein Coding |
| Official Symbol | GPR101 |
| Official Name | G protein-coupled receptor 101 [Source:HGNC Symbol;Acc:HGNC:14963] |
| Ensembl ID | ENSG00000165370 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 101 |
| Synonyms | Gm365,GPCR6,G protein-coupled receptor 101,PAGH2,PITA2,RGD1564196 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the GPR101 gene plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- FUS
- TMEM239
- AGPAT4
- YIPF6
- CDIPT
- C1GALT1
- LMNB2
- MFSD5
- SLC39A9
- GAN
disease
- growth hormone-secreting pituitary adenoma 2
regulated by
- ADCYAP1
- SSB
regulates
role in cell
- growth
- cisplatin sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the GPR101 gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
- adenylate cyclase-activating adrenergic receptor signaling pathway
- positive regulation of MAPK cascade
CELLULAR COMPONENT
Where in the cell the gene product is active
- receptor complex
- plasma membrane
MOLECULAR FUNCTION
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding