Eipr1 Gene Summary [Mouse]

Predicted to be involved in several processes, including endocytic recycling; positive regulation of intracellular transport; and regulation of insulin secretion. Predicted to be located in trans-Golgi network. Predicted to be part of EARP complex and GARP complex. Is expressed in hippocampus; liver; neural retina; and olfactory epithelium. Orthologous to human EIPR1 (EARP complex and GARP complex interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Eipr1
Official Name
EARP complex and GARP complex interacting protein 1 [Source:MGI Symbol;Acc:MGI:1289332]
Ensembl ID
ENSMUSG00000036613
Bio databases IDs NCBI: 380752 Ensembl: ENSMUSG00000036613
Aliases EARP complex and GARP complex interacting protein 1
Synonyms D12Ertd604e, EARP complex and GARP complex interacting protein 1, TSSC1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eipr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • WD40
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • insulin
regulated by
disease
  • major depression
  • schizophrenia
  • angina pectoris

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • trans Golgi network

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Eipr1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of insulin secretion
  • positive regulation of endocytic recycling
  • endocytic recycling
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • trans-Golgi network
  • GARP complex

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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