Exoc1 Gene Summary [Mouse]
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Acts upstream of or within embryo implantation. Predicted to be located in cytoplasm. Predicted to be part of exocyst. Predicted to be active in plasma membrane. Is expressed in fronto-nasal process mesenchyme; mandibular process mesenchyme; and maxillary process mesenchyme. Orthologous to human EXOC1 (exocyst complex component 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Exoc1 |
| Official Name | exocyst complex component 1 [Source:MGI Symbol;Acc:MGI:2445020] |
| Ensembl ID | ENSMUSG00000036435 |
| Bio databases IDs | |
| Aliases | exocyst complex component 1 |
| Synonyms | 2810407P21RIK, A730011E05Rik, BM-102, exocyst complex component 1, SEC3, SEC3L1, SEC3P |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Exoc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Exocyst complex component Sec3
- protein binding
- Pleckstrin homology-like domain
- transporter
- Exocyst complex component SEC3 N-terminal PIP2 binding PH
Pathways
Biological processes and signaling networks where the Exoc1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Exoc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fission
- cytokinesis after mitosis
- vesicle docking involved in exocytosis
- protein transport
- Golgi to plasma membrane transport
- regulation of macroautophagy
- defense response to virus
- exocytosis
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytoplasm
- membrane
- cytosol
- plasma membrane
- exocyst
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- protein binding