Ints7 Gene Summary [Mouse]
Predicted to be involved in DNA damage checkpoint signaling; cellular response to ionizing radiation; and snRNA 3'-end processing. Predicted to be located in chromosome; cytoplasm; and nuclear body. Predicted to be part of integrator complex. Is expressed in central nervous system and retina. Orthologous to human INTS7 (integrator complex subunit 7). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ints7 |
| Official Name | integrator complex subunit 7 [Source:MGI Symbol;Acc:MGI:1924315] |
| Ensembl ID | ENSMUSG00000037461 |
| Bio databases IDs | |
| Aliases | integrator complex subunit 7 |
| Synonyms | 5930412E23Rik, C1orf73, DKFZp434B168, INT7, integrator complex subunit 7, RGD1308014 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ints7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- chromosome
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ints7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage checkpoint
- snRNA processing
- regulation of transcription elongation from RNA polymerase II promoter
- snRNA 3'-end processing
- cellular response to ionizing radiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- cytoplasm
- chromosome
- integrator complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding