Ptpdc1 Gene Summary [Mouse]
The protein encoded by this gene is a centrosomal mitotic phosphatase. This protein has been implicated in centrosomal duplication and cytokinesis. In addition, knockdown of expression levels in non-cycling cells results in extra long cilia, suggesting that this protein may function in regulating cilia length independent of a function in cell cycle control. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
Details
| Type | Protein Coding |
| Official Symbol | Ptpdc1 |
| Official Name | protein tyrosine phosphatase domain containing 1 [Source:MGI Symbol;Acc:MGI:2145430] |
| Ensembl ID | ENSMUSG00000038042 |
| Bio databases IDs | |
| Aliases | protein tyrosine phosphatase domain containing 1 |
| Synonyms | Naa-1, protein tyrosine phosphatase domain containing 1, Protein tyrosine phosphatase domain containing 1 protein isoform 1, PTP9Q22, Ptpcd1, Ptpdc1 predicted |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ptpdc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dual specificity phosphatase, catalytic domain
- Protein tyrosine phosphatase, catalytic domain, undefined specificity
- protein-tyrosine-phoshatase
- phosphatase
- protein binding
- PTP_DSP_cys
- Protein tyrosine phosphatase, catalytic domain motif
Pathways
Biological processes and signaling networks where the Ptpdc1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ptpdc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein tyrosine phosphatase activity