Tmem181a Gene Summary [Mouse]

Predicted to enable toxic substance binding activity. Is expressed in several structures, including cardiovascular system; central nervous system; gut; reproductive system; and trachea. Orthologous to human TMEM181 (transmembrane protein 181). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tmem181a
Official Name
transmembrane protein 181A [Source:MGI Symbol;Acc:MGI:1924356]
Ensembl ID
ENSMUSG00000038141
Bio databases IDs NCBI: 77106 Ensembl: ENSMUSG00000038141
Aliases transmembrane protein 181A
Synonyms 5930418K15RIK, C76977, GPR178, KIAA1423, mKIAA1423, RGD1566403, Tmem181a, transmembrane protein 181, transmembrane protein 181A
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem181a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Wnt-binding factor required for Wnt secretion
  • toxin binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • open-angle glaucoma
  • glaucoma
  • infection by HIV-1
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem181a gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • toxin binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.