TMEM181 Gene Summary [Human]
The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]
Details
| Type | Protein Coding |
| Official Symbol | TMEM181 |
| Official Name | transmembrane protein 181 [Source:HGNC Symbol;Acc:HGNC:20958] |
| Ensembl ID | ENSG00000146433 |
| Bio databases IDs | |
| Aliases | transmembrane protein 181 |
| Synonyms | 5930418K15RIK, C76977, GPR178, KIAA1423, mKIAA1423, RGD1566403, Tmem181a, transmembrane protein 181, transmembrane protein 181A |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM181 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Wnt-binding factor required for Wnt secretion
- toxin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM181 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- toxin binding