Mindy1 Gene Summary [Mouse]
Predicted to enable K48-linked deubiquitinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in nuclear body. Orthologous to human MINDY1 (MINDY lysine 48 deubiquitinase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Mindy1 |
| Official Name | MINDY lysine 48 deubiquitinase 1 [Source:MGI Symbol;Acc:MGI:1922257] |
| Ensembl ID | ENSMUSG00000038712 |
| Bio databases IDs | |
| Aliases | MINDY lysine 48 deubiquitinase 1 |
| Synonyms | 1810005H09Rik, 4930504E06Rik, cI-40, FAM63A, MINDY lysine 48 deubiquitinase 1, mKIAA1390, ni |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mindy1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PXsP motif
- MINDY deubiquitinase
- peptidase
- protein binding
- Serine Proline motif
- cysteine-type carboxypeptidase
- ubiquitin-like-specific protease
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mindy1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- protein K48-linked deubiquitination
Cellular Component
Where in the cell the gene product is active
- nuclear body
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding
- cysteine-type carboxypeptidase activity