Abitram Gene Summary [Mouse]
Enables actin filament binding activity and actin monomer binding activity. Involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Located in several cellular components, including filopodium tip; lamellipodium; and nuclear speck. Is expressed in cartilage; endocrine gland; genitourinary system; nervous system; and trachea. Orthologous to human ABITRAM (actin binding transcription modulator). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abitram |
| Official Name | actin binding transcription modulator [Source:MGI Symbol;Acc:MGI:2677850] |
| Ensembl ID | ENSMUSG00000038827 |
| Bio databases IDs | |
| Aliases | actin binding transcription modulator |
| Synonyms | actin binding transcription modulator, C9orf6, CG-8, FAM206A, Simiate |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abitram often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- actin monomer binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Nucleus
- nuclear speckles
- growth cone
- filopodia
- dendrites
- lamellipodia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Abitram gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of actin filament polymerization
- regulation of filopodium assembly
- dendrite morphogenesis
Cellular Component
Where in the cell the gene product is active
- growth cone
- nucleus
- dendrite
- nuclear speck
- filopodium tip
- lamellipodium
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- protein binding
- actin monomer binding