Tmem214 Gene Summary [Mouse]

Predicted to be involved in apoptotic process. Predicted to be located in cytoplasmic microtubule and cytosol. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in axial skeleton; chondrocranium; otic capsule; and rib. Orthologous to human TMEM214 (transmembrane protein 214). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tmem214
Official Name
transmembrane protein 214 [Source:MGI Symbol;Acc:MGI:1916046]
Ensembl ID
ENSMUSG00000038828
Bio databases IDs NCBI: 68796 Ensembl: ENSMUSG00000038828
Aliases transmembrane protein 214
Synonyms 1110039B18Rik, 4921530J21Rik, RGD1311324, transmembrane protein 214
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem214 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TMEM214, C-terminal, caspase 4 activator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
role in cell
  • apoptosis
  • molecular cleavage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • outer membranes
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • Mitochondria
  • cytosol
  • endoplasmic reticulum membrane
  • cytoplasmic microtubule

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem214 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • apoptotic process

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cytosol
  • Golgi apparatus
  • endoplasmic reticulum
  • cytoplasmic microtubule

Gene-Specific Assays for Results You Can Trust

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