Trhr2 Gene Summary [Mouse]

Predicted to enable thyrotropin-releasing hormone receptor activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in neuronal cell body and plasma membrane. Is expressed in brain; cap mesenchyme; embryo; and female associated reproductive structure. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Trhr2
Official Name
thyrotropin releasing hormone receptor 2 [Source:MGI Symbol;Acc:MGI:2177284]
Ensembl ID
ENSMUSG00000039079
Bio databases IDs NCBI: 170732 Ensembl: ENSMUSG00000039079
Aliases thyrotropin releasing hormone receptor 2
Synonyms LOC120098567, Mlnr, motilin receptor, thyrotropin releasing hormone receptor 2
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trhr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • thyrotropin-releasing hormone receptor
  • Cholecystokinin A receptor, N-terminal
  • 7 transmembrane receptor (rhodopsin family)
  • protein binding
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Trhr2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • phosphatidylinositol polyphosphate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • perikaryon

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.