Atf7ip2 Gene Summary [Mouse]
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; gut; heart; liver; and lung. Orthologous to human ATF7IP2 (activating transcription factor 7 interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atf7ip2 |
| Official Name | activating transcription factor 7 interacting protein 2 [Source:MGI Symbol;Acc:MGI:1922579] |
| Ensembl ID | ENSMUSG00000039200 |
| Bio databases IDs | |
| Aliases | activating transcription factor 7 interacting protein 2 |
| Synonyms | 4930558K11RIK, activating transcription factor 7 interacting protein 2, BC018510, FLJ11507, Get-1, MCAF2, PSM2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atf7ip2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FN3
- Fibronectin-III type domain
- ATF-interacting protein binding domain
- Fibronectin type 3 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atf7ip2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- positive regulation of methylation-dependent chromatin silencing
Cellular Component
Where in the cell the gene product is active
- nucleus
- transcription factor complex
Molecular Function
What the gene product does at the molecular level
- transcription cofactor activity