ATF7IP2 Gene Summary [Human]

Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
ATF7IP2
Official Name
activating transcription factor 7 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:20397]
Ensembl ID
ENSG00000166669
Bio databases IDs NCBI: 80063 Ensembl: ENSG00000166669
Aliases activating transcription factor 7 interacting protein 2
Synonyms 4930558K11RIK, activating transcription factor 7 interacting protein 2, BC018510, FLJ11507, Get-1, MCAF2, PSM2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ATF7IP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FN3
  • Fibronectin-III type domain
  • ATF-interacting protein binding domain
  • Fibronectin type 3 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • prostate cancer
  • COVID-19
  • soft tissue disorder
regulated by
  • 26S proteasome
  • dexamethasone
  • MEIOSIN/STRA8
  • DDIT3
  • DNMT1
role in cell
  • inactivation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ATF7IP2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription, DNA-dependent
  • positive regulation of methylation-dependent chromatin silencing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • transcription factor complex

Molecular Function

What the gene product does at the molecular level
  • transcription cofactor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.