Zup1 Gene Summary [Mouse]
Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Predicted to be located in cytosol and nucleoplasm. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZUP1 (zinc finger containing ubiquitin peptidase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zup1 |
| Official Name | zinc finger containing ubiquitin peptidase 1 [Source:MGI Symbol;Acc:MGI:1919830] |
| Ensembl ID | ENSMUSG00000039531 |
| Bio databases IDs | |
| Aliases | zinc finger containing ubiquitin peptidase 1 |
| Synonyms | 2700019D07Rik, C6orf113, DUB, RGD1307672, zinc finger containing ubiquitin peptidase 1, ZUFSP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zup1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Peptidase family C78
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zup1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding
- metal ion binding