Dnttip2 Gene Summary [Mouse]
Predicted to be involved in RNA processing and ribosomal small subunit biogenesis. Predicted to be located in chromosome and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in early conceptus and embryo. Orthologous to human DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dnttip2 |
| Official Name | deoxynucleotidyltransferase, terminal, interacting protein 2 [Source:MGI Symbol;Acc:MGI:1923173] |
| Ensembl ID | ENSMUSG00000039756 |
| Bio databases IDs | |
| Aliases | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| Synonyms | 4930588M11Rik, deoxynucleotidyltransferase terminal interacting protein 2, deoxynucleotidyltransferase, terminal, interacting protein 2, ERBP, FCF2, HSU15552, LPTS-RP2, RGD1309084, TdIF2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dnttip2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Fcf2 pre-rRNA processing
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- chronic kidney disease
- nonsyndromic cleft lip and palate
- uterine leiomyoma
- leiomyomatosis
role in cell
- expression in
- G1 phase
- processing in
- G2 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- chromosome
- nucleoplasm
- nucleoli
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dnttip2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit biogenesis
- RNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- chromosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding